Diclofenac sodium (Diclofenac Sodium)

Diclofenac sodium is a nonsteroidal anti-inflammatory drug (NSAID) used to treat signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis (arthritis of the spine).

Diclofenac sodium can cause serious problems (such as heart attack or stroke). Your risk can increase when this medication is used for long periods of time and in people who have heart disease. Tell your doctor if you experience chest pain, shortness of breath, weakness, or slurred speech. Also, diclofenac sodium can cause high blood pressure or worsening of existing high blood pressure, and heart failure which can lead to weight gain or edema (swelling). Diclofenac sodium can cause discomfort, ulcers, or bleeding in your stomach or intestines. Your risk can increase with long-term use, smoking, drinking alcohol, older age, or with certain medications. Tell your doctor immediately if you experience abdominal pain or if you have bloody vomit or stools. Long-term use of diclofenac sodium can cause kidney injury. Your risk can increase if you have kidney impairment; heart failure; liver problems; are taking certain medications, including diuretics (water pills) (such as furosemide) or blood/heart medications known as angiotensin-converting enzyme (ACE) inhibitors (such as lisinopril); are dehydrated; or are elderly. Also, diclofenac sodium can cause liver injury. Tell your doctor if you experience nausea, tiredness, weakness, itchiness, yellowing of your skin or whites of your eyes, right upper abdominal tenderness, or “flu-like” symptoms. Diclofenac sodium can cause allergic reactions resembling anaphylaxis (a serious and rapid allergic reaction that may result in death if not immediately treated). Stop taking diclofenac sodium and tell your doctor immediately if you experience difficulty breathing or swelling of your face, mouth, or throat. Tell your doctor immediately if you experience serious skin reactions which can be characterized by a severe rash, fever, or itchiness.