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Prempro (Conjugated Estrogens/Medroxyprogesterone Acetate)

Prempro is a medicine containing the hormones, estrogen and progestin. It is used to treat moderate to severe symptoms of menopause, such as hot flashes and changes in or around your vagina. Prempro also helps to reduce your chances of getting postmenopausal osteoporosis (thin, weak bones).

Estrogens increase your risk of developing cancer of the uterus. Tell your doctor immediately if you experience any unusual vaginal bleeding while you are taking Prempro. Do not take Prempro to prevent heart disease, heart attacks, strokes, or dementia. Taking Prempro can increase your chances of getting heart attacks, strokes, breast cancer, or blood clots. Prempro can also increase your risk of dementia, gallbladder disease, ovarian cancer, visual abnormalities, high blood pressure, pancreatitis (inflammation of the pancreas), or thyroid problems. Talk regularly with your doctor about whether you still need treatment with Prempro. You can lower your chances of serious side effects with Prempro by having a pelvic exam, breast exam, and mammogram (breast x-ray) every year, unless directed by your doctor to have it more often. See your doctor immediately if you get vaginal bleeding while you are taking Prempro. Also, ask your doctor for ways to lower your chances of getting heart disease, especially if you have high blood pressure, high cholesterol, or diabetes, if you are overweight, or if you use tobacco.




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