Ultram (Tramadol HCl)
Ultram is a pain medicine that contains the narcotic painkiller tramadol. Ultram is used to treat moderate to moderately severe pain. Ultram is also available as extended-release tablets (releases medicine into your body throughout the day) called Ultram ER.
Ultram has abuse potential. Mental and physical dependence can occur with the use of Ultram when it is used improperly.
Ultram can cause seizures. The risk is greater if you have a history of seizures, are suffering from alcohol or drug withdrawal, or nervous system infections. Your risk of seizures may also be increased if you are taking antidepressants medications such as monoamine oxidase inhibitors (MAOIs) (such as phenelzine), selective serotonin reuptake inhibitors (SSRIs) (such as fluoxetine or paroxetine), selective norepinephrine reuptake inhibitors (SNRIs) (such as venlafaxine), or tricyclic antidepressants (TCAs) (such as amitriptyline); certain migraine products (such as sumatriptan); or other medicines.
Ultram can cause serotonin syndrome (a potentially life-threatening drug reaction that causes the body to have too much serotonin, a chemical produced by the nerve cells) when you take it alone or in combination with MAOIs, SSRIs, SNRIs, TCAs, or certain migraine products. Tell your doctor right away if you experience mental status changes, an increase in your heart rate and temperature, lack of coordination, overactive reflexes, nausea, vomiting, or diarrhea.
Ultram can cause allergic reactions or anaphylaxis (a serious and rapid allergic reaction that may result in death if not immediately treated). Stop taking Ultram and tell your doctor right away if you develop a rash, difficulty breathing, or swelling of your face, mouth, or throat.
Ultram can cause serious breathing problems that can become life-threatening, especially when it is used in the wrong way.